Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer

Many signaling pathways, including the JAK/STAT3 pathway, are aberrantly activated and associated with ovarian cancer growth and progression. However, inhibition of STAT3 pathway alone was not sufficient to effectively block human ovarian cancer cell survival in vitro, which could be due to the acti...

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Detalles Bibliográficos
Autores principales: Wen, Wei, Han, Ernest S., Dellinger, Thanh H., Wu, Jun, Guo, Yuming, Buettner, Ralf, Horne, David A., Jove, Richard, Yim, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542771/
https://www.ncbi.nlm.nih.gov/pubmed/31141756
http://dx.doi.org/10.1016/j.tranon.2019.05.003

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