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Potential resistant mutations within HBV reverse transcriptase sequences in nucleos(t)ide analogues-experienced patients with hepatitis B virus infection

This study was performed to analyze the potential resistant mutations within HBV reverse transcriptase (RT) sequences against nucleos(t)ide analogues (NA). HBV DNA RT region spanning from amino acid 169 to 250 was amplified and sequenced from 435 HBV patients who experienced NA treatment. Among stud...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoman, Chen, Xianli, Wei, Meijuan, Zhang, Chunyu, Xu, Tao, Liu, Liguan, Xu, Zhengju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542804/
https://www.ncbi.nlm.nih.gov/pubmed/31147594
http://dx.doi.org/10.1038/s41598-019-44604-6

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