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Female-specific decreases in alcohol binge-like drinking resulting from GABA(A) receptor delta-subunit knockdown in the VTA

Binge drinking is short-term drinking that achieves blood alcohol levels of 0.08 g/dl or above. It exhibits well-established sex differences in GABAergic inhibitory neurotransmission, including extrasynaptic δ subunit-containing GABA(A) receptors (δ-GABA(A)Rs) that mediate tonic inhibition, or synap...

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Detalles Bibliográficos
Autores principales: Darnieder, L. M., Melón, L. C., Do, T., Walton, N. L., Miczek, K. A., Maguire, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542821/
https://www.ncbi.nlm.nih.gov/pubmed/31147611
http://dx.doi.org/10.1038/s41598-019-44286-0