A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response

Glycans from microbial pathogens are well known pathogen-associated molecular patterns that are recognized by the host immunity; however, little is known about whether and how mammalian self-glycans activate the host immune response, especially in the context of autoimmune disease. Using biochemical...

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Detalles Bibliográficos
Autores principales: Fermaintt, Charles S., Sano, Kanae, Liu, Zhida, Ishii, Nozomi, Seino, Junichi, Dobbs, Nicole, Suzuki, Tadashi, Fu, Yang-Xin, Lehrman, Mark A., Matsuo, Ichiro, Yan, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542856/
https://www.ncbi.nlm.nih.gov/pubmed/31147550
http://dx.doi.org/10.1038/s41467-019-10319-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542856/
https://www.ncbi.nlm.nih.gov/pubmed/31147550
http://dx.doi.org/10.1038/s41467-019-10319-5

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