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Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications

Medicine is constantly looking for new and improved treatments for diseases, which need to have a high efficacy and be cost-effective, creating a large demand on scientific research to discover such new treatments. One important aspect of any treatment is the ability to be able to target only the il...

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Detalles Bibliográficos
Autores principales: Anderson, Simon D., Gwenin, Vanessa V., Gwenin, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542970/
https://www.ncbi.nlm.nih.gov/pubmed/31147786
http://dx.doi.org/10.1186/s11671-019-3019-6
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author Anderson, Simon D.
Gwenin, Vanessa V.
Gwenin, Christopher D.
author_facet Anderson, Simon D.
Gwenin, Vanessa V.
Gwenin, Christopher D.
author_sort Anderson, Simon D.
collection PubMed
description Medicine is constantly looking for new and improved treatments for diseases, which need to have a high efficacy and be cost-effective, creating a large demand on scientific research to discover such new treatments. One important aspect of any treatment is the ability to be able to target only the illness and not cause harm to another healthy part of the body. For this reason, metallic nanoparticles have been and are currently being extensively researched for their possible medical uses, including medical imaging, antibacterial and antiviral applications. Superparamagnetic metal nanoparticles possess properties that allow them to be directed around the body with a magnetic field or directed to a magnetic implant, which opens up the potential to conjugate various bio-cargos to the nanoparticles that could then be directed for treatment in the body. Here we report on some of the current bio-medical applications of various metal nanoparticles, including single metal nanoparticles, functionalized metal nanoparticles, and core-shell metal nanoparticles using a core of Fe(3)O(4) as well as synthesis methods of these core-shell nanoparticles.
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spelling pubmed-65429702019-06-19 Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications Anderson, Simon D. Gwenin, Vanessa V. Gwenin, Christopher D. Nanoscale Res Lett Nano Review Medicine is constantly looking for new and improved treatments for diseases, which need to have a high efficacy and be cost-effective, creating a large demand on scientific research to discover such new treatments. One important aspect of any treatment is the ability to be able to target only the illness and not cause harm to another healthy part of the body. For this reason, metallic nanoparticles have been and are currently being extensively researched for their possible medical uses, including medical imaging, antibacterial and antiviral applications. Superparamagnetic metal nanoparticles possess properties that allow them to be directed around the body with a magnetic field or directed to a magnetic implant, which opens up the potential to conjugate various bio-cargos to the nanoparticles that could then be directed for treatment in the body. Here we report on some of the current bio-medical applications of various metal nanoparticles, including single metal nanoparticles, functionalized metal nanoparticles, and core-shell metal nanoparticles using a core of Fe(3)O(4) as well as synthesis methods of these core-shell nanoparticles. Springer US 2019-05-30 /pmc/articles/PMC6542970/ /pubmed/31147786 http://dx.doi.org/10.1186/s11671-019-3019-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Nano Review
Anderson, Simon D.
Gwenin, Vanessa V.
Gwenin, Christopher D.
Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title_full Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title_fullStr Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title_full_unstemmed Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title_short Magnetic Functionalized Nanoparticles for Biomedical, Drug Delivery and Imaging Applications
title_sort magnetic functionalized nanoparticles for biomedical, drug delivery and imaging applications
topic Nano Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542970/
https://www.ncbi.nlm.nih.gov/pubmed/31147786
http://dx.doi.org/10.1186/s11671-019-3019-6
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