The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases

Autophagy, a catabolic degradation system, is utilized for destroying and recycling the damaged or unnecessary cellular components. Brain plasticity refers to the remarkable characteristics of brain neurons that change their structure and function according to previous experience. This review was pe...

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Autores principales: Wang, Man-Man, Feng, Ya-Shuo, Yang, Si-Dong, Xing, Ying, Zhang, Jing, Dong, Fang, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542992/
https://www.ncbi.nlm.nih.gov/pubmed/31244604
http://dx.doi.org/10.3389/fncel.2019.00228
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author Wang, Man-Man
Feng, Ya-Shuo
Yang, Si-Dong
Xing, Ying
Zhang, Jing
Dong, Fang
Zhang, Feng
author_facet Wang, Man-Man
Feng, Ya-Shuo
Yang, Si-Dong
Xing, Ying
Zhang, Jing
Dong, Fang
Zhang, Feng
author_sort Wang, Man-Man
collection PubMed
description Autophagy, a catabolic degradation system, is utilized for destroying and recycling the damaged or unnecessary cellular components. Brain plasticity refers to the remarkable characteristics of brain neurons that change their structure and function according to previous experience. This review was performed by searching the relevant articles in databases of SCIENCEDIRECT, PUBMED, and Web of Science, from respective inception to January 2019. Here, we review the neuroprotective effect of autophagy in neurological diseases and the mechanism of autophagy in brain plasticity. Moreover, the mechanism of autophagy in the process of brain plasticity can provide the possibility for the development of new treatment methods in the future, thus benefiting patients with neurological diseases. In summary, autophagy and brain plasticity play important roles in neurological diseases.
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spelling pubmed-65429922019-06-26 The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases Wang, Man-Man Feng, Ya-Shuo Yang, Si-Dong Xing, Ying Zhang, Jing Dong, Fang Zhang, Feng Front Cell Neurosci Neuroscience Autophagy, a catabolic degradation system, is utilized for destroying and recycling the damaged or unnecessary cellular components. Brain plasticity refers to the remarkable characteristics of brain neurons that change their structure and function according to previous experience. This review was performed by searching the relevant articles in databases of SCIENCEDIRECT, PUBMED, and Web of Science, from respective inception to January 2019. Here, we review the neuroprotective effect of autophagy in neurological diseases and the mechanism of autophagy in brain plasticity. Moreover, the mechanism of autophagy in the process of brain plasticity can provide the possibility for the development of new treatment methods in the future, thus benefiting patients with neurological diseases. In summary, autophagy and brain plasticity play important roles in neurological diseases. Frontiers Media S.A. 2019-05-24 /pmc/articles/PMC6542992/ /pubmed/31244604 http://dx.doi.org/10.3389/fncel.2019.00228 Text en Copyright © 2019 Wang, Feng, Yang, Xing, Zhang, Dong and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Wang, Man-Man
Feng, Ya-Shuo
Yang, Si-Dong
Xing, Ying
Zhang, Jing
Dong, Fang
Zhang, Feng
The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title_full The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title_fullStr The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title_full_unstemmed The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title_short The Relationship Between Autophagy and Brain Plasticity in Neurological Diseases
title_sort relationship between autophagy and brain plasticity in neurological diseases
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542992/
https://www.ncbi.nlm.nih.gov/pubmed/31244604
http://dx.doi.org/10.3389/fncel.2019.00228
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