Exploring the overlapping binding sites of ifenprodil and EVT‐101 in GluN2B‐containing NMDA receptors using novel chicken embryo forebrain cultures and molecular modeling

N‐methyl‐d‐aspartate receptors (NMDAR) are widely expressed in the brain. GluN2B subunit‐containing NMDARs has recently attracted significant attention as potential pharmacological targets, with emphasis on the functional properties of allosteric antagonists. We used primary cultures from chicken em...

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Detalles Bibliográficos
Autores principales: Fjelldal, Marthe F., Freyd, Thibaud, Evenseth, Linn M., Sylte, Ingebrigt, Ring, Avi, Paulsen, Ragnhild E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543015/
https://www.ncbi.nlm.nih.gov/pubmed/31164987
http://dx.doi.org/10.1002/prp2.480

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