Secalonic acid D induces cell apoptosis in both sensitive and ABCG2-overexpressing multidrug resistant cancer cells through upregulating c-Jun expression

Secalonic acid D (SAD) could inhibit cell growth in not only sensitive cells but also multidrug resistant (MDR) cells. However, the molecular mechanisms need to be elucidated. Here, we identified that SAD possessed potent cytotoxicity in 3 pairs of MDR and their parental sensitive cells including S1...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Huang, Liyan, Tao, Liyang, Zhang, Jianye, Wang, Fang, Zhang, Xu, Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543021/
https://www.ncbi.nlm.nih.gov/pubmed/31193763
http://dx.doi.org/10.1016/j.apsb.2018.12.006

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