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Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer׳s disease

Gene therapy represents a promising treatment for the Alzheimer׳s disease (AD). However, gene delivery specific to brain lesions through systemic administration remains big challenge. In our previous work, we have developed an siRNA nanocomplex able to be specifically delivered to the amyloid plaque...

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Detalles Bibliográficos
Autores principales:	Guo, Qian, Zheng, Xiaoyao, Yang, Peng, Pang, Xiaoying, Qian, Kang, Wang, Pengzhen, Xu, Shuting, Sheng, Dongyu, Wang, Liuchang, Cao, Jinxu, Lu, Wei, Zhang, Qizhi, Jiang, Xinguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543096/ https://www.ncbi.nlm.nih.gov/pubmed/31193846 http://dx.doi.org/10.1016/j.apsb.2018.12.010

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