Redox control of yeast Sir2 activity is involved in acetic acid resistance and longevity

Yeast Sir2 is an NAD-dependent histone deacetylase related to oxidative stress and aging. In a previous study, we showed that Sir2 is regulated by S-glutathionylation of key cysteine residues located at the catalytic domain. Mutation of these residues results in strains with increased resistance to...

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Detalles Bibliográficos
Autores principales: Vall-llaura, Núria, Mir, Noèlia, Garrido, Lourdes, Vived, Celia, Cabiscol, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543126/
https://www.ncbi.nlm.nih.gov/pubmed/31153040
http://dx.doi.org/10.1016/j.redox.2019.101229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543126/
https://www.ncbi.nlm.nih.gov/pubmed/31153040
http://dx.doi.org/10.1016/j.redox.2019.101229

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