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Massive Biventricular Myocardial Calcification in a Patient with Fulminant Myocarditis Requiring Ventricular Assist Device Support

The natural course of myocardial calcification is unclear. We herein report a case of massive biventricular myocardial calcification associated with fulminant myocarditis and present its natural course. The patient was a 15-year-old boy. Massive calcification was detected in both ventricles on compu...

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Detalles Bibliográficos
Autores principales: Kimura, Yuki, Seguchi, Osamu, K. Kono, Atsushi, Matsumoto, Manabu, Kumai, Yuto, Kuroda, Kensuke, Nakajima, Seiko, Watanabe, Takuya, Matsumoto, Yorihiko, Fukushima, Satsuki, Yanase, Masanobu, Fujita, Tomoyuki, Ishibashi-Ueda, Hatsue, Kobayashi, Junjiro, Fukushima, Norihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543210/
https://www.ncbi.nlm.nih.gov/pubmed/30568151
http://dx.doi.org/10.2169/internalmedicine.2039-18
Descripción
Sumario:The natural course of myocardial calcification is unclear. We herein report a case of massive biventricular myocardial calcification associated with fulminant myocarditis and present its natural course. The patient was a 15-year-old boy. Massive calcification was detected in both ventricles on computed tomography several months after left ventricular assist device placement. Although the calcification gradually regressed, the patient's cardiac function did not recover, and he underwent heart transplantation after a waiting period of 3 years. A histological examination revealed severe fibrosis in both ventricles of the original heart. Myocardial calcification might suggest severe myocardial inflammation and injury in cases of fulminant myocarditis.