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Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats

BACKGROUND: Trimethylamine N-oxide (TMAO) has been shown to be involved in cardiovascular disease (CVD). However, its role in nonalcoholic steatohepatitis (NASH) is unknown. AIM: To determine the effect of TMAO on the progression of NASH. METHODS: A rat model was induced by 16-wk high-fat high-chole...

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Detalles Bibliográficos
Autores principales: Zhao, Ze-Hua, Xin, Feng-Zhi, Zhou, Da, Xue, Ya-Qian, Liu, Xiao-Lin, Yang, Rui-Xu, Pan, Qin, Fan, Jian-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543245/
https://www.ncbi.nlm.nih.gov/pubmed/31171889
http://dx.doi.org/10.3748/wjg.v25.i20.2450