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Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats
BACKGROUND: Trimethylamine N-oxide (TMAO) has been shown to be involved in cardiovascular disease (CVD). However, its role in nonalcoholic steatohepatitis (NASH) is unknown. AIM: To determine the effect of TMAO on the progression of NASH. METHODS: A rat model was induced by 16-wk high-fat high-chole...
Autores principales: | Zhao, Ze-Hua, Xin, Feng-Zhi, Zhou, Da, Xue, Ya-Qian, Liu, Xiao-Lin, Yang, Rui-Xu, Pan, Qin, Fan, Jian-Gao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543245/ https://www.ncbi.nlm.nih.gov/pubmed/31171889 http://dx.doi.org/10.3748/wjg.v25.i20.2450 |
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