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Identification of isoform-selective hydroxamic acid derivatives that potently reactivate HIV from latency

OBJECTIVES: Current antiretroviral therapy can suppress HIV replication, increase CD4 count and result in increased lifespan. However, it cannot eradicate the virus due to the presence of latent provirus in cellular reservoirs, such as resting CD4+ T cells. Using combination latency-reversing agents...

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Detalles Bibliográficos
Autores principales:	Heffern, Elleard FW, Ramani, Rashmi, Marshall, Garland, Kyei, George B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mediscript Ltd 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543484/ https://www.ncbi.nlm.nih.gov/pubmed/31191911

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