Possible clearance of transfusion-acquired nef/LTR-deleted attenuated HIV-1 infection by an elite controller with CCR5 Δ32 heterozygous and HLA-B57 genotype

BACKGROUND: Subject C135 is one of the members of the Sydney Blood Bank Cohort, infected in 1981 through transfusion with attenuated nef/3′ long terminal repeat (LTR)-deleted HIV-1, and has maintained undetectable plasma viral load and steady CD4 cell count, in the absence of therapy. Uniquely, C135...

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Detalles Bibliográficos
Autores principales: Zaunders, John, Dyer, Wayne B, Churchill, Melissa, Munier, C Mee Ling, Cunningham, Philip H, Suzuki, Kazuo, McBride, Kristin, Hey-Nguyen, Will, Koelsch, Kersten, Wang, Bin, Hiener, Bonnie, Palmer, Sarah, Gorry, Paul R, Bailey, Michelle, Xu, Yin, Danta, Mark, Seddiki, Nabila, Cooper, David A, Saksena, Nitin K, Sullivan, John S, Riminton, Sean, Learmont, Jenny, Kelleher, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mediscript Ltd 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543488/
https://www.ncbi.nlm.nih.gov/pubmed/31191910

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