Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABA(A) Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms

THIP (gaboxadol), a superagonist of the δ subunit-containing extrasynaptic GABA(A) receptors, produces persistent neuroplasticity in dopamine (DA) neurons of the ventral tegmental area (VTA), similarly to rewarding drugs of abuse. However, unlike them THIP lacks abuse potential and induces condition...

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Detalles Bibliográficos
Autores principales: de Miguel, Elena, Vekovischeva, Olga, Elsilä, Lauri V., Panhelainen, Anne, Kankuri, Esko, Aitta-aho, Teemu, Korpi, Esa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543524/
https://www.ncbi.nlm.nih.gov/pubmed/31178693
http://dx.doi.org/10.3389/fnmol.2019.00130

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