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Relationship between tumor biomarkers and efficacy in MARIANNE, a phase III study of trastuzumab emtansine ± pertuzumab versus trastuzumab plus taxane in HER2-positive advanced breast cancer

BACKGROUND: The phase III EMILIA and TH3RESA trials demonstrated clinical benefits of trastuzumab emtansine (T-DM1) therapy in patients with previously treated HER2-positive metastatic breast cancer (MBC). Data from these and other trials showed that T-DM1–associated survival benefits were observed...

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Detalles Bibliográficos
Autores principales:	Perez, Edith A., de Haas, Sanne Lysbet, Eiermann, Wolfgang, Barrios, Carlos H., Toi, Masakazu, Im, Young-Hyuck, Conte, Pier Franco, Martin, Miguel, Pienkowski, Tadeusz, Pivot, Xavier B., Burris, Howard A., Stanzel, Sven, Patre, Monika, Ellis, Paul Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543580/ https://www.ncbi.nlm.nih.gov/pubmed/31146717 http://dx.doi.org/10.1186/s12885-019-5687-0

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