Transplantation of CRISPRa system engineered IL10-overexpressing bone marrow-derived mesenchymal stem cells for the treatment of myocardial infarction in diabetic mice

BACKGROUND: Myocardial infarction (MI) is a common cause of mortality in people. Mesenchymal stem cell (MSC) has been shown to exert therapeutic potential to treat myocardial infarction (MI). However, in patients with diabetes, the diabetic environment affected MSCs activity and could impair the eff...

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Detalles Bibliográficos
Autores principales: Meng, Xin, Zheng, Minjuan, Yu, Ming, Bai, Wei, Zuo, Lei, Bu, Xin, Liu, Yi, Xia, Linying, Hu, Jing, Liu, Liwen, Li, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543626/
https://www.ncbi.nlm.nih.gov/pubmed/31164920
http://dx.doi.org/10.1186/s13036-019-0163-6

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