A Hepatitis C Virus DNA Vaccine Encoding a Secreted, Oligomerized Form of Envelope Proteins Is Highly Immunogenic and Elicits Neutralizing Antibodies in Vaccinated Mice

Hepatitis C virus (HCV) persistently infects approximately 71 million people globally. To prevent infection a vaccine which elicits neutralizing antibodies against the virus envelope proteins (E1/E2) which are required for entry into host cells is desirable. DNA vaccines are cost-effective to manufa...

Descripción completa

Detalles Bibliográficos
Autores principales: Masavuli, Makutiro Ghislain, Wijesundara, Danushka K., Underwood, Alexander, Christiansen, Dale, Earnest-Silveira, Linda, Bull, Rowena, Torresi, Joseph, Gowans, Eric J., Grubor-Bauk, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543710/
https://www.ncbi.nlm.nih.gov/pubmed/31178869
http://dx.doi.org/10.3389/fimmu.2019.01145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543710/
https://www.ncbi.nlm.nih.gov/pubmed/31178869
http://dx.doi.org/10.3389/fimmu.2019.01145

Ejemplares similares