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A Hepatitis C Virus DNA Vaccine Encoding a Secreted, Oligomerized Form of Envelope Proteins Is Highly Immunogenic and Elicits Neutralizing Antibodies in Vaccinated Mice

Hepatitis C virus (HCV) persistently infects approximately 71 million people globally. To prevent infection a vaccine which elicits neutralizing antibodies against the virus envelope proteins (E1/E2) which are required for entry into host cells is desirable. DNA vaccines are cost-effective to manufa...

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Detalles Bibliográficos
Autores principales:	Masavuli, Makutiro Ghislain, Wijesundara, Danushka K., Underwood, Alexander, Christiansen, Dale, Earnest-Silveira, Linda, Bull, Rowena, Torresi, Joseph, Gowans, Eric J., Grubor-Bauk, Branka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543710/ https://www.ncbi.nlm.nih.gov/pubmed/31178869 http://dx.doi.org/10.3389/fimmu.2019.01145

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