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Computational Identification of Novel Kir6 Channel Inhibitors

KATP channels consist of four Kir6.x pore–forming subunits and four regulatory sulfonylurea receptor (SUR) subunits. These channels couple the metabolic state of the cell to membrane excitability and play a key role in physiological processes such as insulin secretion in the pancreas, protection of...

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Detalles Bibliográficos
Autores principales:	Chen, Xingyu, Garon, Arthur, Wieder, Marcus, Houtman, Marien J. C., Zangerl-Plessl, Eva-Maria, Langer, Thierry, van der Heyden, Marcel A. G., Stary-Weinzinger, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543810/ https://www.ncbi.nlm.nih.gov/pubmed/31178728 http://dx.doi.org/10.3389/fphar.2019.00549

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