Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation

Acute kidney injury (AKI) is a frequent and serious complication of orthotopic liver transplantation (OLT), with a significant impact on mortality, graft survival, and chronic kidney disease. Currently, the diagnosis of AKI is based on changes in serum creatinine, which is a late marker, usually ris...

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Autores principales: Lewandowska, Lidia, Małyszko, Jolanta, Matuszkiewicz-Rowińska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543872/
https://www.ncbi.nlm.nih.gov/pubmed/31110167
http://dx.doi.org/10.12659/AOT.914975
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author Lewandowska, Lidia
Małyszko, Jolanta
Matuszkiewicz-Rowińska, Joanna
author_facet Lewandowska, Lidia
Małyszko, Jolanta
Matuszkiewicz-Rowińska, Joanna
author_sort Lewandowska, Lidia
collection PubMed
description Acute kidney injury (AKI) is a frequent and serious complication of orthotopic liver transplantation (OLT), with a significant impact on mortality, graft survival, and chronic kidney disease. Currently, the diagnosis of AKI is based on changes in serum creatinine, which is a late marker, usually rising when there is already significant damage to the renal parenchyma. During the last 2 decades, various biomarkers have been studied in many clinical situations, mostly after cardiac surgery, in drug-induced AKI, or in sepsis. The present article summarizes the data on those biomarkers that have been evaluated for the prediction of AKI in patients undergoing OLT.
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spelling pubmed-65438722019-06-13 Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation Lewandowska, Lidia Małyszko, Jolanta Matuszkiewicz-Rowińska, Joanna Ann Transplant Review Paper Acute kidney injury (AKI) is a frequent and serious complication of orthotopic liver transplantation (OLT), with a significant impact on mortality, graft survival, and chronic kidney disease. Currently, the diagnosis of AKI is based on changes in serum creatinine, which is a late marker, usually rising when there is already significant damage to the renal parenchyma. During the last 2 decades, various biomarkers have been studied in many clinical situations, mostly after cardiac surgery, in drug-induced AKI, or in sepsis. The present article summarizes the data on those biomarkers that have been evaluated for the prediction of AKI in patients undergoing OLT. International Scientific Literature, Inc. 2019-05-21 /pmc/articles/PMC6543872/ /pubmed/31110167 http://dx.doi.org/10.12659/AOT.914975 Text en © Ann Transplant, 2019 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Review Paper
Lewandowska, Lidia
Małyszko, Jolanta
Matuszkiewicz-Rowińska, Joanna
Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title_full Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title_fullStr Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title_full_unstemmed Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title_short Urinary and Serum Biomarkers for Prediction of Acute Kidney Injury in Patients Undergoing Liver Transplantation
title_sort urinary and serum biomarkers for prediction of acute kidney injury in patients undergoing liver transplantation
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543872/
https://www.ncbi.nlm.nih.gov/pubmed/31110167
http://dx.doi.org/10.12659/AOT.914975
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