Cargando…
Discovery of Coumarin as Microtubule Affinity-Regulating Kinase 4 Inhibitor That Sensitize Hepatocellular Carcinoma to Paclitaxel
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers worldwide. Nowadays, pharmacological therapy for HCC is in urgent needs. Paclitaxel is an effective drug against diverse solid tumors, but commonly resisted in HCC patients. We recently have disclosed that microtubule affinity-regul...
Autores principales: | Shen, Xianyan, Liu, Xuesha, Wan, Shunli, Fan, Xin, He, Huaiyu, Wei, Rong, Pu, Wenchen, Peng, Yong, Wang, Chun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543911/ https://www.ncbi.nlm.nih.gov/pubmed/31179271 http://dx.doi.org/10.3389/fchem.2019.00366 |
Ejemplares similares
-
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis
por: Wang, Lulu, et al.
Publicado: (2021) -
Discovery of 4-(2-(dimethylamino)ethoxy)benzohydrazide derivatives as prospective microtubule affinity regulating kinase 4 inhibitors
por: Khan, Nashrah Sharif, et al.
Publicado: (2020) -
Identification of potent inhibitors of microtubule affinity regulating kinase for inhibition of tau hyperphosphorylation
por: Levy, Alison, et al.
Publicado: (2013) -
Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones
por: Voura, Maria, et al.
Publicado: (2019) -
Effect of c-Abl tyrosine kinase on the cellular response to paclitaxel-induced microtubule damage
por: Nehmé, A, et al.
Publicado: (2000)