Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals

Mixed cryoglobulinaemia (MCG) is one of the most severe extrahepatic hepatitis C virus (HCV)-associated complications, and could involve several organs, including the kidney. MCG prognosis relies on HCV response to antiviral treatment and has changed over the last years, especially after the introdu...

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Detalles Bibliográficos
Autores principales: Barbieri, Diego, García-Prieto, Ana, Torres, Esther, Verde, Eduardo, Goicoechea, Marian, Luño, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Glomerular Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543977/
https://www.ncbi.nlm.nih.gov/pubmed/31198535
http://dx.doi.org/10.1093/ckj/sfy055
Descripción
Sumario:Mixed cryoglobulinaemia (MCG) is one of the most severe extrahepatic hepatitis C virus (HCV)-associated complications, and could involve several organs, including the kidney. MCG prognosis relies on HCV response to antiviral treatment and has changed over the last years, especially after the introduction of new direct acting antivirals (DAA). MCG persistence despite sustained virological response (SVR) is uncommon and has a poorly known meaning and prognosis. We report a case of a patient with chronic HCV infection treated with DAA who developed MCG vasculitis despite the SVR.

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