Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals

Mixed cryoglobulinaemia (MCG) is one of the most severe extrahepatic hepatitis C virus (HCV)-associated complications, and could involve several organs, including the kidney. MCG prognosis relies on HCV response to antiviral treatment and has changed over the last years, especially after the introdu...

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Autores principales: Barbieri, Diego, García-Prieto, Ana, Torres, Esther, Verde, Eduardo, Goicoechea, Marian, Luño, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Glomerular Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543977/
https://www.ncbi.nlm.nih.gov/pubmed/31198535
http://dx.doi.org/10.1093/ckj/sfy055
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author Barbieri, Diego
García-Prieto, Ana
Torres, Esther
Verde, Eduardo
Goicoechea, Marian
Luño, José
author_facet Barbieri, Diego
García-Prieto, Ana
Torres, Esther
Verde, Eduardo
Goicoechea, Marian
Luño, José
author_sort Barbieri, Diego
collection PubMed
description Mixed cryoglobulinaemia (MCG) is one of the most severe extrahepatic hepatitis C virus (HCV)-associated complications, and could involve several organs, including the kidney. MCG prognosis relies on HCV response to antiviral treatment and has changed over the last years, especially after the introduction of new direct acting antivirals (DAA). MCG persistence despite sustained virological response (SVR) is uncommon and has a poorly known meaning and prognosis. We report a case of a patient with chronic HCV infection treated with DAA who developed MCG vasculitis despite the SVR.
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spelling pubmed-65439772019-06-13 Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals Barbieri, Diego García-Prieto, Ana Torres, Esther Verde, Eduardo Goicoechea, Marian Luño, José Clin Kidney J Glomerular Disease Mixed cryoglobulinaemia (MCG) is one of the most severe extrahepatic hepatitis C virus (HCV)-associated complications, and could involve several organs, including the kidney. MCG prognosis relies on HCV response to antiviral treatment and has changed over the last years, especially after the introduction of new direct acting antivirals (DAA). MCG persistence despite sustained virological response (SVR) is uncommon and has a poorly known meaning and prognosis. We report a case of a patient with chronic HCV infection treated with DAA who developed MCG vasculitis despite the SVR. Oxford University Press 2018-07-09 /pmc/articles/PMC6543977/ /pubmed/31198535 http://dx.doi.org/10.1093/ckj/sfy055 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Glomerular Disease
Barbieri, Diego
García-Prieto, Ana
Torres, Esther
Verde, Eduardo
Goicoechea, Marian
Luño, José
Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title_full Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title_fullStr Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title_full_unstemmed Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title_short Mixed cryoglobulinaemia vasculitis after sustained hepatitis C virological response with direct-acting antivirals
title_sort mixed cryoglobulinaemia vasculitis after sustained hepatitis c virological response with direct-acting antivirals
topic Glomerular Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543977/
https://www.ncbi.nlm.nih.gov/pubmed/31198535
http://dx.doi.org/10.1093/ckj/sfy055
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