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Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology

Dermatitis herpetiformis and linear IgA bullous dermatosis are autoimmune diseases that present with pruritic urticarial papules and plaques, with formation of vesicles and blisters of subepidermal location, mediated by IgA antibodies. Mucosal lesions are present only in linear IgA bullous dermatosi...

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Autores principales: do Vale, Everton Carlos Siviero, Dimatos, Oscar Cardoso, Porro, Adriana Maria, Santi, Claudia Giuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544034/
https://www.ncbi.nlm.nih.gov/pubmed/31166403
http://dx.doi.org/10.1590/abd1806-4841.2019940208
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author do Vale, Everton Carlos Siviero
Dimatos, Oscar Cardoso
Porro, Adriana Maria
Santi, Claudia Giuli
author_facet do Vale, Everton Carlos Siviero
Dimatos, Oscar Cardoso
Porro, Adriana Maria
Santi, Claudia Giuli
author_sort do Vale, Everton Carlos Siviero
collection PubMed
description Dermatitis herpetiformis and linear IgA bullous dermatosis are autoimmune diseases that present with pruritic urticarial papules and plaques, with formation of vesicles and blisters of subepidermal location, mediated by IgA antibodies. Mucosal lesions are present only in linear IgA bullous dermatosis. The elaboration of this consensus consisted of a brief presentation of the different aspects of these dermatoses and, above all, of an updated literature review on the various therapeutic options that were discussed and compared with the authors’ experience, aiming at the treatment orientation of these diseases in Brazil. Dermatitis herpetiformis is a cutaneous manifestation of celiac disease, and can be controlled with a gluten-free diet and dapsone. On the other hand, linear IgA bullous dermatosis arises spontaneously or is triggered by drugs, and can be controlled with dapsone, but often requires the association of systemic corticosteroids and eventually immunosuppressants.
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spelling pubmed-65440342019-06-12 Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology do Vale, Everton Carlos Siviero Dimatos, Oscar Cardoso Porro, Adriana Maria Santi, Claudia Giuli An Bras Dermatol Bullous Dermatoses Dermatitis herpetiformis and linear IgA bullous dermatosis are autoimmune diseases that present with pruritic urticarial papules and plaques, with formation of vesicles and blisters of subepidermal location, mediated by IgA antibodies. Mucosal lesions are present only in linear IgA bullous dermatosis. The elaboration of this consensus consisted of a brief presentation of the different aspects of these dermatoses and, above all, of an updated literature review on the various therapeutic options that were discussed and compared with the authors’ experience, aiming at the treatment orientation of these diseases in Brazil. Dermatitis herpetiformis is a cutaneous manifestation of celiac disease, and can be controlled with a gluten-free diet and dapsone. On the other hand, linear IgA bullous dermatosis arises spontaneously or is triggered by drugs, and can be controlled with dapsone, but often requires the association of systemic corticosteroids and eventually immunosuppressants. Sociedade Brasileira de Dermatologia 2019 /pmc/articles/PMC6544034/ /pubmed/31166403 http://dx.doi.org/10.1590/abd1806-4841.2019940208 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Bullous Dermatoses
do Vale, Everton Carlos Siviero
Dimatos, Oscar Cardoso
Porro, Adriana Maria
Santi, Claudia Giuli
Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title_full Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title_fullStr Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title_full_unstemmed Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title_short Consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear IgA bullous dermatosis - Brazilian Society of Dermatology
title_sort consensus on the treatment of autoimmune bullous dermatoses: dermatitis herpetiformis and linear iga bullous dermatosis - brazilian society of dermatology
topic Bullous Dermatoses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544034/
https://www.ncbi.nlm.nih.gov/pubmed/31166403
http://dx.doi.org/10.1590/abd1806-4841.2019940208
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