A Dose Escalation Study of Trientine Plus Carboplatin and Pegylated Liposomal Doxorubicin in Women With a First Relapse of Epithelial Ovarian, Tubal, and Peritoneal Cancer Within 12 Months After Platinum-Based Chemotherapy

Background: Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related deaths worldwide. Preclinical studies found that copper-lowering agents could re-sensitize platinum-resistant cancer cells by enhancing the human copper transporter 1 (hCtr1)-mediated uptake of platinum....

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Detalles Bibliográficos
Autores principales: Huang, Yu-Fang, Kuo, Macus Tien, Liu, Yi-Sheng, Cheng, Ya-Min, Wu, Pei-Ying, Chou, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544081/
https://www.ncbi.nlm.nih.gov/pubmed/31179244
http://dx.doi.org/10.3389/fonc.2019.00437

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