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Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment
Background: Fc-mannose-binding lectin (FcMBL), an engineered version of the blood opsonin MBL that contains the carbohydrate recognition domain (CRD) and flexible neck regions of MBL fused to the Fc portion of human IgG1, has been shown to bind various microbes and pathogen-associated molecular patt...
Autores principales: | Seiler, Benjamin T., Cartwright, Mark, Dinis, Alexandre L. M., Duffy, Shannon, Lombardo, Patrick, Cartwright, David, Super, Elana H., Lanzaro, Jacqueline, Dugas, Kristen, Super, Michael, Ingber, Donald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544136/ https://www.ncbi.nlm.nih.gov/pubmed/31275563 http://dx.doi.org/10.12688/f1000research.17447.1 |
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