Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

The immune-mediated tissue destruction of graft-vs-host disease (GvHD) remains a major barrier to greater use of hematopoietic stem cell transplantation (HSCT). Mesenchymal stem cells (MSCs) have intrinsic immunosuppressive qualities and are being actively investigated as a therapeutic strategy for...

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Detalles Bibliográficos
Autores principales: Ozay, E. Ilker, Vijayaraghavan, Jyothi, Gonzalez-Perez, Gabriela, Shanthalingam, Sudarvili, Sherman, Heather L., Garrigan, Daniel T., Chandiran, Karthik, Torres, Joe A., Osborne, Barbara A., Tew, Gregory N., Slukvin, Igor I., Macdonald, Ross A., Kelly, Kilian, Minter, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544140/
https://www.ncbi.nlm.nih.gov/pubmed/30738321
http://dx.doi.org/10.1016/j.scr.2019.101401

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