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Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response

Although the aggregation of the amyloid-β peptide (Aβ) into amyloid fibrils is a well-established hallmark of Alzheimer’s disease, the complex mechanisms linking this process to neurodegeneration are still incompletely understood. The nematode worm C. elegans is a valuable model organism through whi...

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Detalles Bibliográficos
Autores principales: Sinnige, Tessa, Ciryam, Prashanth, Casford, Samuel, Dobson, Christopher M., de Bono, Mario, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544271/
https://www.ncbi.nlm.nih.gov/pubmed/31150491
http://dx.doi.org/10.1371/journal.pone.0217746

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