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Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response
Although the aggregation of the amyloid-β peptide (Aβ) into amyloid fibrils is a well-established hallmark of Alzheimer’s disease, the complex mechanisms linking this process to neurodegeneration are still incompletely understood. The nematode worm C. elegans is a valuable model organism through whi...
Autores principales: | Sinnige, Tessa, Ciryam, Prashanth, Casford, Samuel, Dobson, Christopher M., de Bono, Mario, Vendruscolo, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544271/ https://www.ncbi.nlm.nih.gov/pubmed/31150491 http://dx.doi.org/10.1371/journal.pone.0217746 |
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