Addition of an oligoglutamate domain to bone morphogenic protein 2 confers binding to hydroxyapatite materials and induces osteoblastic signaling

Nonautologous bone grafts have limited osteoinductive potential and thus there is substantial interest in reconstituting these graft materials with osteogenic factors such as bone morphogenic protein 2 (BMP2). However, one limitation of this approach is that BMP2 is typically weakly bound to the gra...

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Detalles Bibliográficos
Autores principales: Curry, Andrew S., McPherson, David T., Barlow, Abby M., Pensa, Nicholas W., Reddy, Michael S., Bellis, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544276/
https://www.ncbi.nlm.nih.gov/pubmed/31150531
http://dx.doi.org/10.1371/journal.pone.0217766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544276/
https://www.ncbi.nlm.nih.gov/pubmed/31150531
http://dx.doi.org/10.1371/journal.pone.0217766

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