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Addition of an oligoglutamate domain to bone morphogenic protein 2 confers binding to hydroxyapatite materials and induces osteoblastic signaling
Nonautologous bone grafts have limited osteoinductive potential and thus there is substantial interest in reconstituting these graft materials with osteogenic factors such as bone morphogenic protein 2 (BMP2). However, one limitation of this approach is that BMP2 is typically weakly bound to the gra...
Autores principales: | Curry, Andrew S., McPherson, David T., Barlow, Abby M., Pensa, Nicholas W., Reddy, Michael S., Bellis, Susan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544276/ https://www.ncbi.nlm.nih.gov/pubmed/31150531 http://dx.doi.org/10.1371/journal.pone.0217766 |
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