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Pathogenicity of the H1N1 influenza virus enhanced by functional synergy between the NP(V100I) and NA(D248N) pair
By comparing and measuring covariations of viral protein sequences from isolates of the 2009 pH1N1 influenza A virus (IAV), specific substitutions that co-occur in the NP-NA pair were identified. To investigate the effect of these co-occurring substitution pairs, the V100I substitution in NP and the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544299/ https://www.ncbi.nlm.nih.gov/pubmed/31150476 http://dx.doi.org/10.1371/journal.pone.0217691 |