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Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance
Human papillomaviruses (HPV) have genotype-specific disease associations, with high-risk alpha types causing at least 5% of all human cancers. Despite these conspicuous differences, our data show that high- and low- risk HPV types use similar approaches for genome maintenance and persistence. During...
Autores principales: | Murakami, Isao, Egawa, Nagayasu, Griffin, Heather, Yin, Wen, Kranjec, Christian, Nakahara, Tomomi, Kiyono, Tohru, Doorbar, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544336/ https://www.ncbi.nlm.nih.gov/pubmed/31083694 http://dx.doi.org/10.1371/journal.ppat.1007755 |
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