Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

Cyclic dinucleotides (CDNs) play central roles in bacterial homeostasis and virulence as nucleotide second messengers. Bacterial CDNs also elicit immune responses during infection when they are detected by pattern recognition receptors in animal cells. Here, we performed a systematic biochemical scr...

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Detalles Bibliográficos
Autores principales: Whiteley, Aaron T., Eaglesham, James B., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Lowey, Brianna, Nieminen, Eric A., Danilchanka, Olga, King, David S., Lee, Amy S.Y., Mekalanos, John J., Kranzusch, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544370/
https://www.ncbi.nlm.nih.gov/pubmed/30787435
http://dx.doi.org/10.1038/s41586-019-0953-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544370/
https://www.ncbi.nlm.nih.gov/pubmed/30787435
http://dx.doi.org/10.1038/s41586-019-0953-5

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