Reality check for transposon enhancers

Hundreds of retrovirus-like sequences have features that suggest they might be gene enhancers, but only a small fraction displays gene-regulating activity in experiments on mouse stem cells.

Detalles Bibliográficos
Autores principales: Brind'Amour, Julie, Mager, Dixie L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544458/
https://www.ncbi.nlm.nih.gov/pubmed/31148541
http://dx.doi.org/10.7554/eLife.47900
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author Brind'Amour, Julie
Mager, Dixie L
author_facet Brind'Amour, Julie
Mager, Dixie L
author_sort Brind'Amour, Julie
collection PubMed
description Hundreds of retrovirus-like sequences have features that suggest they might be gene enhancers, but only a small fraction displays gene-regulating activity in experiments on mouse stem cells.
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spelling pubmed-65444582019-06-12 Reality check for transposon enhancers Brind'Amour, Julie Mager, Dixie L eLife Chromosomes and Gene Expression Hundreds of retrovirus-like sequences have features that suggest they might be gene enhancers, but only a small fraction displays gene-regulating activity in experiments on mouse stem cells. eLife Sciences Publications, Ltd 2019-05-31 /pmc/articles/PMC6544458/ /pubmed/31148541 http://dx.doi.org/10.7554/eLife.47900 Text en © 2019, Brind'Amour and Mager http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Chromosomes and Gene Expression
Brind'Amour, Julie
Mager, Dixie L
Reality check for transposon enhancers
title Reality check for transposon enhancers
title_full Reality check for transposon enhancers
title_fullStr Reality check for transposon enhancers
title_full_unstemmed Reality check for transposon enhancers
title_short Reality check for transposon enhancers
title_sort reality check for transposon enhancers
topic Chromosomes and Gene Expression
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544458/
https://www.ncbi.nlm.nih.gov/pubmed/31148541
http://dx.doi.org/10.7554/eLife.47900
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