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Yeast-secreted, dried and food-admixed monomeric IgA prevents gastrointestinal infection in a piglet model
A scalably manufacturable oral antibody technology that can interfere with gastrointestinal (GI) targets is needed. Contrary to the complex native secretory IgA, we achieve this using a single-gene encoded monomeric-IgA-like antibody, composed of camelid VHH fused to IgA Fc (mVHH-IgA). This can be p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544532/ https://www.ncbi.nlm.nih.gov/pubmed/30936561 http://dx.doi.org/10.1038/s41587-019-0070-x |