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Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials

Epidemiological studies indicate an inverse association of coffee consumption with risk of type 2 diabetes mellitus. However, studies to determine the clinical effects of coffee consumption on the glucose metabolism biomarkers remain uncertain. The aim of this systematic review was to evaluate the e...

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Detalles Bibliográficos
Autores principales: Reis, Caio E.G., Dórea, José G., da Costa, Teresa H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544578/
https://www.ncbi.nlm.nih.gov/pubmed/31193893
http://dx.doi.org/10.1016/j.jtcme.2018.01.001
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author Reis, Caio E.G.
Dórea, José G.
da Costa, Teresa H.M.
author_facet Reis, Caio E.G.
Dórea, José G.
da Costa, Teresa H.M.
author_sort Reis, Caio E.G.
collection PubMed
description Epidemiological studies indicate an inverse association of coffee consumption with risk of type 2 diabetes mellitus. However, studies to determine the clinical effects of coffee consumption on the glucose metabolism biomarkers remain uncertain. The aim of this systematic review was to evaluate the effects of coffee consumption on glucose metabolism. A search of electronic databases (PubMed and Web of Science) was performed identifying studies published until September 2017. Eight clinical trials (n = 247 subjects) were identified for analyses. Participants and studies characteristics, main findings, and study quality (Jadad Score) were reported. Short-term (1–3 h) and long-term (2–16 weeks) studies were summarized separately. Short-term studies showed that consumption of caffeinated coffee may increase the area under the curve for glucose response, while for long-term studies, caffeinated coffee may improve the glycaemic metabolism by reducing the glucose curve and increasing the insulin response. The findings suggest that consumption of caffeinated coffee may lead to unfavourable acute effects; however, an improvement on glucose metabolism was found on long-term follow-up.
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spelling pubmed-65445782019-06-05 Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials Reis, Caio E.G. Dórea, José G. da Costa, Teresa H.M. J Tradit Complement Med Review Article Epidemiological studies indicate an inverse association of coffee consumption with risk of type 2 diabetes mellitus. However, studies to determine the clinical effects of coffee consumption on the glucose metabolism biomarkers remain uncertain. The aim of this systematic review was to evaluate the effects of coffee consumption on glucose metabolism. A search of electronic databases (PubMed and Web of Science) was performed identifying studies published until September 2017. Eight clinical trials (n = 247 subjects) were identified for analyses. Participants and studies characteristics, main findings, and study quality (Jadad Score) were reported. Short-term (1–3 h) and long-term (2–16 weeks) studies were summarized separately. Short-term studies showed that consumption of caffeinated coffee may increase the area under the curve for glucose response, while for long-term studies, caffeinated coffee may improve the glycaemic metabolism by reducing the glucose curve and increasing the insulin response. The findings suggest that consumption of caffeinated coffee may lead to unfavourable acute effects; however, an improvement on glucose metabolism was found on long-term follow-up. Elsevier 2018-05-03 /pmc/articles/PMC6544578/ /pubmed/31193893 http://dx.doi.org/10.1016/j.jtcme.2018.01.001 Text en © 2018 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Reis, Caio E.G.
Dórea, José G.
da Costa, Teresa H.M.
Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title_full Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title_fullStr Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title_full_unstemmed Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title_short Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials
title_sort effects of coffee consumption on glucose metabolism: a systematic review of clinical trials
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544578/
https://www.ncbi.nlm.nih.gov/pubmed/31193893
http://dx.doi.org/10.1016/j.jtcme.2018.01.001
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