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Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration

BACKGROUND AND OBJECTIVES: Inhibition of Abelson (Abl) tyrosine kinase as a therapeutic target has been gaining attention in neurodegeneration. Post-mortem Alzheimer’s and Parkinson’s disease brains show that the levels of several other tyrosine kinases, including Discoidin Domain Receptors (DDR1/2)...

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Detalles Bibliográficos
Autores principales:	Fowler, Alan J., Hebron, Michaeline, Missner, Alexander A., Wang, Ruchong, Gao, Xiaokong, Kurd-Misto, Bahjat T., Liu, Xiaoguang, Moussa, Charbel E.-H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544596/ https://www.ncbi.nlm.nih.gov/pubmed/30919310 http://dx.doi.org/10.1007/s40268-019-0266-z

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