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Learning from droplet flows in microfluidic channels using deep neural networks
A non-intrusive method is presented for measuring different fluidic properties in a microfluidic chip by optically monitoring the flow of droplets. A neural network is used to extract the desired information from the images of the droplets. We demonstrate the method in two applications: measurement...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544611/ https://www.ncbi.nlm.nih.gov/pubmed/31148559 http://dx.doi.org/10.1038/s41598-019-44556-x |
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author | Hadikhani, Pooria Borhani, Navid H. Hashemi, S. Mohammad Psaltis, Demetri |
author_facet | Hadikhani, Pooria Borhani, Navid H. Hashemi, S. Mohammad Psaltis, Demetri |
author_sort | Hadikhani, Pooria |
collection | PubMed |
description | A non-intrusive method is presented for measuring different fluidic properties in a microfluidic chip by optically monitoring the flow of droplets. A neural network is used to extract the desired information from the images of the droplets. We demonstrate the method in two applications: measurement of the concentration of each component of a water/alcohol mixture, and measurement of the flow rate of the same mixture. A large number of droplet images are recorded and used to train deep neural networks (DNN) to predict the flow rate or the concentration. It is shown that this method can be used to quantify the concentrations of each component with a 0.5% accuracy and the flow rate with a resolution of 0.05 ml/h. The proposed method can in principle be used to measure other properties of the fluid such as surface tension and viscosity. |
format | Online Article Text |
id | pubmed-6544611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-65446112019-06-09 Learning from droplet flows in microfluidic channels using deep neural networks Hadikhani, Pooria Borhani, Navid H. Hashemi, S. Mohammad Psaltis, Demetri Sci Rep Article A non-intrusive method is presented for measuring different fluidic properties in a microfluidic chip by optically monitoring the flow of droplets. A neural network is used to extract the desired information from the images of the droplets. We demonstrate the method in two applications: measurement of the concentration of each component of a water/alcohol mixture, and measurement of the flow rate of the same mixture. A large number of droplet images are recorded and used to train deep neural networks (DNN) to predict the flow rate or the concentration. It is shown that this method can be used to quantify the concentrations of each component with a 0.5% accuracy and the flow rate with a resolution of 0.05 ml/h. The proposed method can in principle be used to measure other properties of the fluid such as surface tension and viscosity. Nature Publishing Group UK 2019-05-31 /pmc/articles/PMC6544611/ /pubmed/31148559 http://dx.doi.org/10.1038/s41598-019-44556-x Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Hadikhani, Pooria Borhani, Navid H. Hashemi, S. Mohammad Psaltis, Demetri Learning from droplet flows in microfluidic channels using deep neural networks |
title | Learning from droplet flows in microfluidic channels using deep neural networks |
title_full | Learning from droplet flows in microfluidic channels using deep neural networks |
title_fullStr | Learning from droplet flows in microfluidic channels using deep neural networks |
title_full_unstemmed | Learning from droplet flows in microfluidic channels using deep neural networks |
title_short | Learning from droplet flows in microfluidic channels using deep neural networks |
title_sort | learning from droplet flows in microfluidic channels using deep neural networks |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544611/ https://www.ncbi.nlm.nih.gov/pubmed/31148559 http://dx.doi.org/10.1038/s41598-019-44556-x |
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