Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC

BACKGROUND: Epithelial to mesenchymal transition (EMT) is a well-characterized process of cell plasticity that may involve metabolic rewiring. In cancer, EMT is associated with malignant progression, tumor heterogeneity, and therapy resistance. In this study, we investigated the role of succinate de...

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Detalles Bibliográficos
Autores principales: Røsland, Gro V., Dyrstad, Sissel E., Tusubira, Deusdedit, Helwa, Reham, Tan, Tuan Zea, Lotsberg, Maria L., Pettersen, Ina K. N., Berg, Anna, Kindt, Charlotte, Hoel, Fredrik, Jacobsen, Kirstine, Arason, Ari J., Engelsen, Agnete S. T., Ditzel, Henrik J., Lønning, Per E., Krakstad, Camilla, Thiery, Jean P., Lorens, James B., Knappskog, Stian, Tronstad, Karl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544948/
https://www.ncbi.nlm.nih.gov/pubmed/31164982
http://dx.doi.org/10.1186/s40170-019-0197-8

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