Autologous stem cell transplantation in refractory Crohn’s disease – low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study

BACKGROUND: Intestinal inflammation in Crohn’s disease (CD) is caused by mucosal immune system reactivity to luminal antigen and results in debilitating symptoms, reduced quality of life, impaired work productivity and significant health care costs. Not all patients respond to conventional and biolo...

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Detalles Bibliográficos
Autores principales: Snowden, John A., Hawkey, Chris, Hind, Daniel, Swaby, Lizzie, Mellor, Katie, Emsley, Richard, Mandefield, Laura, Lee, Ellen, Badoglio, Manuela, Polge, Emmanuelle, Labopin, Myriam, Gribben, John, Pockley, A. Graham, Foulds, Gemma A., Lobo, Alan, Travis, Simon, Parkes, Miles, Satsangi, Jack, Papaioannou, Diana, Lindsay, James O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544952/
https://www.ncbi.nlm.nih.gov/pubmed/31151436
http://dx.doi.org/10.1186/s12876-019-0992-2

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