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Human Leukocyte Antigen (HLA) class I and II datasets for sudanese

Sudan is located in the heart of Africa and surrounded by eight countries with people of different ethnic origins. Historical records show that the population of the Sudan is a mixture of Arabic, West Asian Arabic and sub-Saharan African elements. The present survey provides data on allele lineages,...

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Autores principales: Dafalla, Ameer Mohamed, Edinur, Hisham Atan, Abdelwahed, Mohammed, Elemam, Almutaz Abbas, Ibrahim, Amel Abdeen, Mohamadani, Ahmed, Magzoub, Mubarak, ElGhazali, Gehad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545336/
https://www.ncbi.nlm.nih.gov/pubmed/31193964
http://dx.doi.org/10.1016/j.dib.2019.104027
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author Dafalla, Ameer Mohamed
Edinur, Hisham Atan
Abdelwahed, Mohammed
Elemam, Almutaz Abbas
Ibrahim, Amel Abdeen
Mohamadani, Ahmed
Magzoub, Mubarak
ElGhazali, Gehad
author_facet Dafalla, Ameer Mohamed
Edinur, Hisham Atan
Abdelwahed, Mohammed
Elemam, Almutaz Abbas
Ibrahim, Amel Abdeen
Mohamadani, Ahmed
Magzoub, Mubarak
ElGhazali, Gehad
author_sort Dafalla, Ameer Mohamed
collection PubMed
description Sudan is located in the heart of Africa and surrounded by eight countries with people of different ethnic origins. Historical records show that the population of the Sudan is a mixture of Arabic, West Asian Arabic and sub-Saharan African elements. The present survey provides data on allele lineages, and haplotype frequencies of Human Leukocyte Antigen (HLA) class I (HLA-A and HLA-B) and class II (HLA-DR and –HLA-DQ) loci in 11 Sudanese populations. The sampled individuals are all local transplant donors who provided informed consent for HLA analyses on their blood samples and were registered at National Cancer Institute, University of Gezira, Wad Medani. The HLA class I and II data reported here can be subjected for future analyses of genetic structure and health in Sudan. These include as reference datasets for identifying the association between HLA and diseases and for designing donor recruitment strategies.
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spelling pubmed-65453362019-06-06 Human Leukocyte Antigen (HLA) class I and II datasets for sudanese Dafalla, Ameer Mohamed Edinur, Hisham Atan Abdelwahed, Mohammed Elemam, Almutaz Abbas Ibrahim, Amel Abdeen Mohamadani, Ahmed Magzoub, Mubarak ElGhazali, Gehad Data Brief Genetics, Genomics and Molecular Biology Sudan is located in the heart of Africa and surrounded by eight countries with people of different ethnic origins. Historical records show that the population of the Sudan is a mixture of Arabic, West Asian Arabic and sub-Saharan African elements. The present survey provides data on allele lineages, and haplotype frequencies of Human Leukocyte Antigen (HLA) class I (HLA-A and HLA-B) and class II (HLA-DR and –HLA-DQ) loci in 11 Sudanese populations. The sampled individuals are all local transplant donors who provided informed consent for HLA analyses on their blood samples and were registered at National Cancer Institute, University of Gezira, Wad Medani. The HLA class I and II data reported here can be subjected for future analyses of genetic structure and health in Sudan. These include as reference datasets for identifying the association between HLA and diseases and for designing donor recruitment strategies. Elsevier 2019-05-21 /pmc/articles/PMC6545336/ /pubmed/31193964 http://dx.doi.org/10.1016/j.dib.2019.104027 Text en © 2019 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Genetics, Genomics and Molecular Biology
Dafalla, Ameer Mohamed
Edinur, Hisham Atan
Abdelwahed, Mohammed
Elemam, Almutaz Abbas
Ibrahim, Amel Abdeen
Mohamadani, Ahmed
Magzoub, Mubarak
ElGhazali, Gehad
Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title_full Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title_fullStr Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title_full_unstemmed Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title_short Human Leukocyte Antigen (HLA) class I and II datasets for sudanese
title_sort human leukocyte antigen (hla) class i and ii datasets for sudanese
topic Genetics, Genomics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545336/
https://www.ncbi.nlm.nih.gov/pubmed/31193964
http://dx.doi.org/10.1016/j.dib.2019.104027
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