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Insulin autoimmune syndrome possibly caused by coenzyme Q10
A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplem...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Association of Rural Medicine
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545416/ https://www.ncbi.nlm.nih.gov/pubmed/31191778 http://dx.doi.org/10.2185/jrm.2975 |
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author | Kusano, Yoshiro |
author_facet | Kusano, Yoshiro |
author_sort | Kusano, Yoshiro |
collection | PubMed |
description | A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplements for three months. Her human leukocyte antigen serotype was DR4. After stopping coenzyme Q10, her hypoglycemia disappeared and immunoreactive insulin and insulin antibody levels normalized. Based on the above, she was diagnosed with insulin autoimmune syndrome caused by coenzyme Q10. It is necessary to be aware of the onset of insulin autoimmune syndrome due to coenzyme Q10. Its pathogenesis requires clarification. |
format | Online Article Text |
id | pubmed-6545416 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Japanese Association of Rural Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-65454162019-06-12 Insulin autoimmune syndrome possibly caused by coenzyme Q10 Kusano, Yoshiro J Rural Med Case Report A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplements for three months. Her human leukocyte antigen serotype was DR4. After stopping coenzyme Q10, her hypoglycemia disappeared and immunoreactive insulin and insulin antibody levels normalized. Based on the above, she was diagnosed with insulin autoimmune syndrome caused by coenzyme Q10. It is necessary to be aware of the onset of insulin autoimmune syndrome due to coenzyme Q10. Its pathogenesis requires clarification. The Japanese Association of Rural Medicine 2019-05-30 2019-05 /pmc/articles/PMC6545416/ /pubmed/31191778 http://dx.doi.org/10.2185/jrm.2975 Text en ©2019 The Japanese Association of Rural Medicine This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kusano, Yoshiro Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title | Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title_full | Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title_fullStr | Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title_full_unstemmed | Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title_short | Insulin autoimmune syndrome possibly caused by coenzyme Q10 |
title_sort | insulin autoimmune syndrome possibly caused by coenzyme q10 |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545416/ https://www.ncbi.nlm.nih.gov/pubmed/31191778 http://dx.doi.org/10.2185/jrm.2975 |
work_keys_str_mv | AT kusanoyoshiro insulinautoimmunesyndromepossiblycausedbycoenzymeq10 |