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Insulin autoimmune syndrome possibly caused by coenzyme Q10

A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplem...

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Detalles Bibliográficos
Autor principal: Kusano, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Association of Rural Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545416/
https://www.ncbi.nlm.nih.gov/pubmed/31191778
http://dx.doi.org/10.2185/jrm.2975
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author Kusano, Yoshiro
author_facet Kusano, Yoshiro
author_sort Kusano, Yoshiro
collection PubMed
description A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplements for three months. Her human leukocyte antigen serotype was DR4. After stopping coenzyme Q10, her hypoglycemia disappeared and immunoreactive insulin and insulin antibody levels normalized. Based on the above, she was diagnosed with insulin autoimmune syndrome caused by coenzyme Q10. It is necessary to be aware of the onset of insulin autoimmune syndrome due to coenzyme Q10. Its pathogenesis requires clarification.
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spelling pubmed-65454162019-06-12 Insulin autoimmune syndrome possibly caused by coenzyme Q10 Kusano, Yoshiro J Rural Med Case Report A 52-year-old woman was transported for reduced consciousness. Her blood glucose was only 19 mg/dL, but her blood immunoreactive insulin and insulin antibody levels were high at 250 μU/mL and 50 U/mL, respectively. She had no history of insulin treatment, but she had been taking coenzyme Q10 supplements for three months. Her human leukocyte antigen serotype was DR4. After stopping coenzyme Q10, her hypoglycemia disappeared and immunoreactive insulin and insulin antibody levels normalized. Based on the above, she was diagnosed with insulin autoimmune syndrome caused by coenzyme Q10. It is necessary to be aware of the onset of insulin autoimmune syndrome due to coenzyme Q10. Its pathogenesis requires clarification. The Japanese Association of Rural Medicine 2019-05-30 2019-05 /pmc/articles/PMC6545416/ /pubmed/31191778 http://dx.doi.org/10.2185/jrm.2975 Text en ©2019 The Japanese Association of Rural Medicine This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kusano, Yoshiro
Insulin autoimmune syndrome possibly caused by coenzyme Q10
title Insulin autoimmune syndrome possibly caused by coenzyme Q10
title_full Insulin autoimmune syndrome possibly caused by coenzyme Q10
title_fullStr Insulin autoimmune syndrome possibly caused by coenzyme Q10
title_full_unstemmed Insulin autoimmune syndrome possibly caused by coenzyme Q10
title_short Insulin autoimmune syndrome possibly caused by coenzyme Q10
title_sort insulin autoimmune syndrome possibly caused by coenzyme q10
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545416/
https://www.ncbi.nlm.nih.gov/pubmed/31191778
http://dx.doi.org/10.2185/jrm.2975
work_keys_str_mv AT kusanoyoshiro insulinautoimmunesyndromepossiblycausedbycoenzymeq10