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Collateral damage: benchmarking off-target effects in genome editing

This editorial discusses what levels of off-target effects can be tolerated in genome editing, in the context of various types of applications.

Detalles Bibliográficos
Autor principal: Carroll, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545683/
https://www.ncbi.nlm.nih.gov/pubmed/31159845
http://dx.doi.org/10.1186/s13059-019-1725-0
Descripción
Sumario:This editorial discusses what levels of off-target effects can be tolerated in genome editing, in the context of various types of applications.