Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type. However, there has been little consensus on genetic and epigenetic signatures of the long-term survival outliers of...

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Detalles Bibliográficos
Autores principales: Hwang, Taeyoung, Mathios, Dimitrios, McDonald, Kerrie L., Daris, Irene, Park, Sung-Hye, Burger, Peter C., Kim, Sojin, Dho, Yun-Sik, Carolyn, Hruban, Bettegowda, Chetan, Shin, Joo Heon, Lim, Michael, Park, Chul-Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545689/
https://www.ncbi.nlm.nih.gov/pubmed/31159876
http://dx.doi.org/10.1186/s40478-019-0744-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545689/
https://www.ncbi.nlm.nih.gov/pubmed/31159876
http://dx.doi.org/10.1186/s40478-019-0744-0

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