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A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery
BACKGROUND: Host factors of influenza virus replication are often found in key topological positions within protein-protein interaction networks. This work explores how protein states can be manipulated through controllability analysis: the determination of the minimum manipulation needed to drive t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545738/ https://www.ncbi.nlm.nih.gov/pubmed/31159726 http://dx.doi.org/10.1186/s12859-019-2917-z |