Cargando…

CD150(high) CD4 T cells and CD150(high) regulatory T cells regulate hematopoietic stem cell quiescence via CD73

Various extrinsic signals tightly control hematopoietic stem cell quiescence. Our recent study showed that hematopoietic stem cells are regulated by a special FoxP3(+) regulatory T-cell population with high expression of a hematopoietic stem cell marker, CD150. Extracellular adenosine generated via...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirata, Yuichi, Kakiuchi, Miwako, Robson, Simon C, Fujisaki, Joji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545860/
https://www.ncbi.nlm.nih.gov/pubmed/30545927
http://dx.doi.org/10.3324/haematol.2018.198283