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Cholesterol Crystals in Hepatocyte Lipid Droplets Are Strongly Associated With Human Nonalcoholic Steatohepatitis

It is unclear what drives the development of fibrosing nonalcoholic steatohepatitis (NASH). We aimed to determine whether cholesterol crystallization within hepatocyte lipid droplets (LDs) distinguishes patients with fibrosing NASH from patients with isolated hepatic steatosis and to study pathways...

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Detalles Bibliográficos
Autores principales:	Ioannou, George N., Landis, Charles S., Jin, Ga‐Young, Haigh, W. Geoffrey, Farrell, Geoffrey C., Kuver, Rahul, Lee, Sum P., Savard, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545865/ https://www.ncbi.nlm.nih.gov/pubmed/31168512 http://dx.doi.org/10.1002/hep4.1348

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