Cargando…
Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of th...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545875/ https://www.ncbi.nlm.nih.gov/pubmed/31198854 http://dx.doi.org/10.1515/pp-2019-0004 |
_version_ | 1783423463001686016 |
---|---|
author | Glatz, Torben Horvath, Philipp Lang, Sven A. Archid, Rami Nadiradze, Giorgi |
author_facet | Glatz, Torben Horvath, Philipp Lang, Sven A. Archid, Rami Nadiradze, Giorgi |
author_sort | Glatz, Torben |
collection | PubMed |
description | BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of the procedure, since most patients had previous surgery. Potential pitfalls include non-access because of adhesions, bowel access lesions and postoperative subcutaneous toxic emphysema. METHODS: We propose a technique, the “finger-access technique” that might prevent largely these pitfalls. A minilaparotomy of 3 cm is performed in the midline, a finger introduced into the abdomen and a 5-mm double-balloon trocar (no Hasson trocar) is placed under finger protection at some distance of the first incision. The fascia of the minilaparotomy, not the skin, is then closed. The abdomen is insufflated with CO(2) and tightness is controlled with saline solution in the minilaparotomy. A second 10–12 mm trocar is then introduced under videoscopic control. The first trocar is then visualized through the second one to exclude a bowel lesion during first access. RESULTS AND CONCLUSIONS: In our hands, this access technique has shown to be safe and effective. |
format | Online Article Text |
id | pubmed-6545875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | De Gruyter |
record_format | MEDLINE/PubMed |
spelling | pubmed-65458752019-06-13 Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen Glatz, Torben Horvath, Philipp Lang, Sven A. Archid, Rami Nadiradze, Giorgi Pleura Peritoneum Research Article BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of the procedure, since most patients had previous surgery. Potential pitfalls include non-access because of adhesions, bowel access lesions and postoperative subcutaneous toxic emphysema. METHODS: We propose a technique, the “finger-access technique” that might prevent largely these pitfalls. A minilaparotomy of 3 cm is performed in the midline, a finger introduced into the abdomen and a 5-mm double-balloon trocar (no Hasson trocar) is placed under finger protection at some distance of the first incision. The fascia of the minilaparotomy, not the skin, is then closed. The abdomen is insufflated with CO(2) and tightness is controlled with saline solution in the minilaparotomy. A second 10–12 mm trocar is then introduced under videoscopic control. The first trocar is then visualized through the second one to exclude a bowel lesion during first access. RESULTS AND CONCLUSIONS: In our hands, this access technique has shown to be safe and effective. De Gruyter 2019-03-21 /pmc/articles/PMC6545875/ /pubmed/31198854 http://dx.doi.org/10.1515/pp-2019-0004 Text en © 2019 Glatz et al., published by De Gruyter http://creativecommons.org/licenses/by/4.0 This work is licensed under the Creative Commons Attribution 4.0 Public License. |
spellingShingle | Research Article Glatz, Torben Horvath, Philipp Lang, Sven A. Archid, Rami Nadiradze, Giorgi Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title | Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title_full | Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title_fullStr | Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title_full_unstemmed | Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title_short | Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen |
title_sort | staging laparoscopy and pressurized intraperitoneal aerosol chemotherapy (pipac) for peritoneal metastasis: safe access to the abdomen |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545875/ https://www.ncbi.nlm.nih.gov/pubmed/31198854 http://dx.doi.org/10.1515/pp-2019-0004 |
work_keys_str_mv | AT glatztorben staginglaparoscopyandpressurizedintraperitonealaerosolchemotherapypipacforperitonealmetastasissafeaccesstotheabdomen AT horvathphilipp staginglaparoscopyandpressurizedintraperitonealaerosolchemotherapypipacforperitonealmetastasissafeaccesstotheabdomen AT langsvena staginglaparoscopyandpressurizedintraperitonealaerosolchemotherapypipacforperitonealmetastasissafeaccesstotheabdomen AT archidrami staginglaparoscopyandpressurizedintraperitonealaerosolchemotherapypipacforperitonealmetastasissafeaccesstotheabdomen AT nadiradzegiorgi staginglaparoscopyandpressurizedintraperitonealaerosolchemotherapypipacforperitonealmetastasissafeaccesstotheabdomen |