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Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen

BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of th...

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Autores principales: Glatz, Torben, Horvath, Philipp, Lang, Sven A., Archid, Rami, Nadiradze, Giorgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545875/
https://www.ncbi.nlm.nih.gov/pubmed/31198854
http://dx.doi.org/10.1515/pp-2019-0004
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author Glatz, Torben
Horvath, Philipp
Lang, Sven A.
Archid, Rami
Nadiradze, Giorgi
author_facet Glatz, Torben
Horvath, Philipp
Lang, Sven A.
Archid, Rami
Nadiradze, Giorgi
author_sort Glatz, Torben
collection PubMed
description BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of the procedure, since most patients had previous surgery. Potential pitfalls include non-access because of adhesions, bowel access lesions and postoperative subcutaneous toxic emphysema. METHODS: We propose a technique, the “finger-access technique” that might prevent largely these pitfalls. A minilaparotomy of 3 cm is performed in the midline, a finger introduced into the abdomen and a 5-mm double-balloon trocar (no Hasson trocar) is placed under finger protection at some distance of the first incision. The fascia of the minilaparotomy, not the skin, is then closed. The abdomen is insufflated with CO(2) and tightness is controlled with saline solution in the minilaparotomy. A second 10–12 mm trocar is then introduced under videoscopic control. The first trocar is then visualized through the second one to exclude a bowel lesion during first access. RESULTS AND CONCLUSIONS: In our hands, this access technique has shown to be safe and effective.
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spelling pubmed-65458752019-06-13 Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen Glatz, Torben Horvath, Philipp Lang, Sven A. Archid, Rami Nadiradze, Giorgi Pleura Peritoneum Research Article BACKGROUND: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of the procedure, since most patients had previous surgery. Potential pitfalls include non-access because of adhesions, bowel access lesions and postoperative subcutaneous toxic emphysema. METHODS: We propose a technique, the “finger-access technique” that might prevent largely these pitfalls. A minilaparotomy of 3 cm is performed in the midline, a finger introduced into the abdomen and a 5-mm double-balloon trocar (no Hasson trocar) is placed under finger protection at some distance of the first incision. The fascia of the minilaparotomy, not the skin, is then closed. The abdomen is insufflated with CO(2) and tightness is controlled with saline solution in the minilaparotomy. A second 10–12 mm trocar is then introduced under videoscopic control. The first trocar is then visualized through the second one to exclude a bowel lesion during first access. RESULTS AND CONCLUSIONS: In our hands, this access technique has shown to be safe and effective. De Gruyter 2019-03-21 /pmc/articles/PMC6545875/ /pubmed/31198854 http://dx.doi.org/10.1515/pp-2019-0004 Text en © 2019 Glatz et al., published by De Gruyter http://creativecommons.org/licenses/by/4.0 This work is licensed under the Creative Commons Attribution 4.0 Public License.
spellingShingle Research Article
Glatz, Torben
Horvath, Philipp
Lang, Sven A.
Archid, Rami
Nadiradze, Giorgi
Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title_full Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title_fullStr Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title_full_unstemmed Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title_short Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
title_sort staging laparoscopy and pressurized intraperitoneal aerosol chemotherapy (pipac) for peritoneal metastasis: safe access to the abdomen
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545875/
https://www.ncbi.nlm.nih.gov/pubmed/31198854
http://dx.doi.org/10.1515/pp-2019-0004
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